Product Overview
- Product Name: Undenatured Type II Collagen
- Synonyms: Undenatured type II collagen, UC-II collagen, type 2 collagen
- Appearance: White to pale yellow powder
- Odor: Slight characteristic odor; no fishy smell
- Water Solubility: Practically insoluble in water
Note: Unlike Hydrolyzed Type II Collagen, Undenatured Type II Collagen retains its natural triple-helical structure through a low-temperature processing method; this structure is the basis for its joint-protective efficacy, which is mediated by the mechanism of oral immune tolerance.
What is Undenatured Type II Collagen?
- Derived primarily from chicken sternal cartilage and extracted using a low-temperature enzymatic process, Undenatured Type II Collagen is a premium, functional ingredient for joint health.
- Its uniqueness lies in the preservation of its intact triple-helical structure and active antigenic epitopes, enabling it to fundamentally alleviate joint inflammation.
- Thanks to its core advantages—specifically, its ultra-low effective dosage and ability to provide anti-inflammatory repair at the source—Undenatured Type II Collagen has become a key ingredient in dietary supplements designed for joint repair.
Why choose Highassay?
- Highassay is a Chinese supplier of Undenatured Type II Collagen raw materials, consistently providing high-purity UC-II ingredients.
- We offer Undenatured Type II Collagen in both granular and powder forms to meet the requirements of diverse application scenarios.
- Highassay supports bulk wholesale, custom specifications, and technical guidance on formulations. We welcome inquiries from global health supplement brands and manufacturers regarding samples and the latest product pricing.
Application of Undenatured Type II Collagen
- Traditional applications:Dietary supplements (most commonly in capsule or tablet form) designed to improve and maintain bone and joint health.
- New directions: Diversified functional foods and beverages, such as gummies and powders.
- Combination formulations: Can be combined with ingredients like glucosamine, chondroitin, calcium, and bone peptides to create products with synergistic effects.
Specification of Undenatured Type II Collagen
- Specification of Undenatured Type II Collagen
| Item | Specification |
| Undenatured Type II Collagen, g/100g | ≥ 26.0 |
| Protein (on drybasis), g/100g | ≥ 60.0 |
| Appearance | White to paleyellow powder, no caking |
| Odor & Taste | Characteristic flavor and odor, no offodors |
| Moisture, g/100g | ≤ 10.0 |
| Ash, g/100g | ≤ 8.0 |
| Total Aerobic Bacteria, CFU/g | ≤ 1000 |
| Coliforms | ＜ 3.0 (MPN/g) |
| Molds & Yeasts, CFU/g | ≤ 50 |
| Pathogens (Salmonella, Staphylococcus aureus) | Negative in 25 g |
| Lead (as Pb), mg/kg | ≤ 0.5 |
| Cadmium (as Cd), mg/kg | ≤ 0.1 |
| Total Arsenic (as As), mg/kg | ≤ 0.5 |
| Chromium (as Cr), mg/kg | ≤ 2.0 |
| Total Mercury (as Hg), mg/kg | ≤ 0.1 |
UC-II retains its intact triple-helical active structure and antigenic epitopes, achieving anti-inflammatory repair through immunomodulation; it is a high-efficacy functional ingredient. In contrast, hydrolyzed collagen merely provides amino acid nutrition without targeted anti-inflammatory or reparative effects, making it suitable only for basic maintenance.
Undenatured Type II collagen does not work through nutritional accumulation; instead, it regulates joint inflammation at the source via a unique mechanism of intestinal immune tolerance. The standard 40mg/day dosage is clinically validated to deliver stable, highly targeted efficacy.
It is primarily suited for high-precision, high-stability functional products such as capsules and tablets, targeting the professional joint repair market.
Undenatured Type II collagen represents only the active component within the total protein content. Total protein encompasses both the undenatured Type II collagen (which retains its triple-helical structure) and denatured collagen (where the structure has unraveled during processing). The remaining content—calculated on a dry-weight basis—consists of ash, trace amounts of fat, and naturally occurring cartilage carbohydrates.
Product Practical Information
Documentation
- A full set of testing and export documentation is available for each batch, including COA, MSDS, and HPLC analysis data confirming the content of undenatured Type II collagen.
Packaging & Storage
- Packaging: 1 kg/bag; 25 kg/drum (with food-grade PE inner liner).
- Storage: Store in a sealed container in a cool, dry, and well-ventilated area; avoid direct sunlight and moisture.
- Shelf Life: 36 months (under standard storage conditions).
Sample Policy
- Free samples are available; please contact our customer service team for details on how to request them.
Minimum Order Quantity
- MOQ: 100 kg; small trial orders are available for R&D formulation testing.
Unsure about model selection? Read the blog：《Type II Collagen Selection Guide》
