A Brief Introduction to Pyridoxal-5-Phosphate Monohydrate
- Product Name : Pyridoxal-5-Phosphate Monohydrate
- English aliases: PLP Monohydrate, Pyridoxal 5′-phosphate hydrate, 5′-Phosphopyridoxal monohydrate,Pyridoxal 5 Phosphate, P5P, Vitamin B6 active form, P5P monohydrate
- Industry Abbreviations: PLP·H₂O, PLP-MH
- Other language names German: Pyridoxal-5-phosphat-Monohydrat; French: Pyridoxal-5-phosphate monohydraté; Spanish: Piridoxal-5-fosfato monohidrato
- CAS number 41468-25-1
- Molecular formula: C₈H₁₀NO₆P·H₂O
- Molecular weight :265.16 g/mol
- Product Grade :Pharmaceutical grade, food grade, industrial grade, cosmetic grade
- Main uses: Nutritional supplements, food additives, pharmaceutical intermediates, cosmetic raw materials, industrial auxiliaries
- Supplier: Changzhou Highassay Chemical Co., Ltd.
Physical and Chemical Properties of Pyridoxal-5-Phosphate Monohydrate
- Appearance and smell : Yellow to orange-yellow crystalline powder, odorless or with a slight special odor.
- Solubility: It is readily soluble in water (solubility of approximately 10 g/100 mL at 25°C), slightly soluble in ethanol, and insoluble in organic solvents such as ether and chloroform.
- Boiling point: Decomposition (decomposes at approximately 250°C, with no definite boiling point).
- Melting point: 233-236℃ (decomposes)
- Density: 1.68 g/cm³ (solid crystal density)
- pH value (1% aqueous solution): 2.5-3.5 (1% aqueous solution)
- Purity :≥98% (Pharmaceutical Grade)
- Other features:
Stability :Store in a cool, dry place where it is stable, avoiding high temperatures, humidity, and light.
Danger: Low toxicity or practically non-toxic; some products may cause slight irritation.
Emergency Response ： Skin contact: Rinse immediately with plenty of water;
Ingestion: Seek immediate medical attention.
Supplementary Technical Details of 5-Pyridoxal monohydrate
- Production methods: It is mainly prepared by pyridoxine (vitamin B6) through oxidation and phosphorylation, followed by crystallization purification to obtain monohydrate; high-purity products are separated using chromatographic techniques.
- Acute toxicity (LD50): Oral LD50 in rats: >5000 mg/kg (practically non-toxic); Intraperitoneal LD50 in mice: 1500-2000 mg/kg
- Chronic toxicity: Long-term use shows no significant cumulative toxicity and meets the standards of food additives GB 14880 and pharmaceutical grade USP.
- Upstream and downstream products (raw materials): Pyridoxine, phosphoric acid, oxidizing agents (such as nitric acid), catalysts
- Upstream and downstream products (downstream): Vitamin B6 injection, nutritional supplements, enzyme preparations, diagnostic kits
- Quality Standards: Compliant with relevant standards such as USP, EP, and GB (subject to adjustment based on product level).
- Detection methods :HPLC, UV, IR, etc. (adjusted according to product characteristics)
- Transportation methods: Sea freight, air freight, and express delivery (depending on customer needs)
- Payment methods: T/T, L/C, Western Union, etc. (negotiable)
- Certification status: ISO9001, GMP, kosher halal etc. (depending on company qualifications)
- Technical Support: Provide MSDS, TDS, COA, product application technical guidance and solutions
Packaging & Storage of Pyridoxal-5-Phosphate Monohydrate
- Packaging 25kg/fiber drum (lined with polyethylene bag), or according to customer requirements
- Storage Store in a cool, dry, and well-ventilated warehouse; avoid direct sunlight and moisture
- Shelf Life 24 months from the production date under proper storage conditions
- CAS number 41468-25-1
- Molecular formula C₈H₁₀NO₆P·H₂O
- molecular weight 265.16 g/mol
- Implementation Standards Enterprise standards or national standards(USP/BP/EP/CP)
- Precautions Avoid storing with strong oxidizers, strong acids, or strong alkalis; wear protective equipment during operation.
- After-sales service Provides COA and MSDS; free returns and exchanges for quality issues; technical support.
Applications of Pyridoxal-5-Phosphate Monohydrate
- Pharmaceutical Field:
* Pharmaceutical-grade P5P raw material can be directly used to prepare oral and injectable formulations for the treatment of symptoms caused by vitamin B6 deficiency, such as seborrheic dermatitis, chapped lips, and peripheral neuritis.
* Pyridoxal-5-phosphate monohydrate is a key ingredient in liver-protective medications or supplements, possessing powerful metabolic regulatory and cell-protective functions, and assisting in improving abnormal liver function.
* Pyridoxal 5 Phosphate plays an indispensable coenzyme role in heme synthesis. It can not only be used as an active ingredient in the treatment of specific types of anemia, but also as a pharmaceutical excipient or enhancer in conventional anti-anemia drug formulations.
*P5P is a core ingredient in high-end medical aesthetic repair products. It can regulate the deep metabolic processes of cells and reduce post-operative redness and allergic reactions.
- Food Sector:
* Food-grade Food-grade pyridoxal 5-phosphate can be added as an essential nutrient fortifier to infant formula, rice cereal, and other products according to standards, providing the necessary vitamin B6 and contributing to amino acid metabolism and nervous system development.
* Pyridoxal-5-phosphate monohydrate is added to functional beverages such as sports drinks and energy drinks to help improve post-exercise performance and recovery speed.
* As a raw material for P5P dietary supplements, it can be used to produce health foods, utilizing P5P’s role in neurotransmitter synthesis to help regulate bodily functions.
* P5P monohydrate can also be used in special-purpose formula foods, such as those for people with malnutrition, post-operative recovery, and liver disease patients.
- Cosmetics Field：
Pyridoxal-5-phosphate monohydrate is added as an active ingredient to high-end, gentle, or acne-prone skin care products (such as repairing creams and oil-controlling cleansers). It helps improve skin condition (anti-inflammatory, brightening, moisturizing, anti-aging, etc.), and the products meet natural certification requirements and are gentle and non-irritating.
- Animal Feed：
Pyridoxal-5-phosphate monohydrate, as the active form of vitamin B6, is a readily available nutritional fortifier. It can be added to various animal feeds, including those for aquaculture, young livestock and poultry, fur animals, and pets, to improve animal health and enhance their physiological functions while ensuring metabolic health.
- Research or Diagnostic Fields：
Pyridoxal-5-Phosphate Monohydrate can be used as a tool, target, and research object in research fields; it can also be used as an indicator or reagent in diagnostic fields.
