Product Overview
- Product Name: Pantethine (D-Pantethine)
- CAS: 16816-67-4
- Molecular Formula: C22H42N4O8S2
- Molecular Weight: 554.72
- EINECS: 240-842-8
- Applications: Raw material for dietary supplements and cosmetics
What is Pantethine?
Pantethine is the active dimeric derivative of vitamin B5 (pantothenic acid) and serves as a direct precursor to coenzyme A (CoA) in the body.
In its raw form, pantethine is a viscous, hygroscopic liquid that is sensitive to light, temperature, and humidity; proper storage is recommended to ensure product stability. It is primarily used in high-end dietary supplement formulations and for laboratory research.
Highassay’s Pantethine
Highassay offers pantethine in three mainstream forms: 80% liquid concentrate, 50% carrier-based powder, and >95% high-purity powder for research applications.
Food-grade Pantethine
We primarily supply two forms of pantethine raw materials—80% liquid concentrate and 50% powder—to meet the requirements of various production scenarios.
Pantethine 80% Liquid Concentrate
- Typically a colorless to pale yellow, transparent, viscous liquid with a high active ingredient content (80% in H₂O). It is suitable for production lines equipped to handle liquid raw materials.
- This form is commonly used in dietary supplements and skincare products because the liquid material is easy to handle, add, and blend uniformly.
Pantethine 50% Powder
- Our 50% powder is a carrier-adsorbed product derived from liquid pantethine, developed to meet specific needs.
- It contains 50% active ingredient, with the remainder consisting of carrier excipients. Its advantages include ease of precise weighing and mixing.
Research-grade pantethine
We also offer high-purity (≥95%) research-grade pantethine. This solid powder form facilitates precise weighing and solution preparation, maximizing the reliability and reproducibility of experimental results.
Application of Pantethine
The common applications of Pantethine generally fall into three categories: raw materials for dietary supplements, ingredients for cosmetics, and specialized materials for scientific research.
- Dietary supplements: Pantethine is processed into various forms, such as tablets, capsules, and softgels.
- Cosmetic ingredients: It is added to skincare products for its moisturizing, antioxidant, and skin-brightening effects.
- Scientific research: It is used in applications such as cell experiments, biochemical research, and analytical testing, or as a reference standard.
Specification of Pantethine
- Specification of Pantethine
Test Item | Specification Standard |
| Solution Concentration | 80% in H₂O |
| Assay (on anhydrous basis) | ≥ 98.0%(calculated on an anhydrous basis) |
| Water Content | 18.0% ~ 22.0% |
| Appearance | Colorless to pale yellow transparent viscous liquid |
| Solubility | Freely soluble in water (up to 50 mg/mL) |
| Optical Rotation | [α]²⁰: +15.0° ~ +18.0° |
| Heavy Metals | ≤ 10 ppm |
| Arsenic | ≤ 1 ppm |
| Ash (Residue on Ignition) | ≤ 0.10% |
| Methanol Residue | ≤ 0.3% |
| Total Aerobic Bacterial Count | ≤ 5000 cfu/g |
| Yeast & Mold | ≤ 25 cfu/g |
| Coliform Bacteria | ≤ 40 MPN/100g |
Liquid is the standard form of Pantethine; however, to facilitate the production of hard capsules and tablets, the liquid raw material is adsorbed onto carriers—such as microcrystalline cellulose or silicon dioxide—to create a powder or granular product.
We provide a complete set of qualification documents, including the COA, MSDS, and test reports; please contact us via email regarding any other required information.
The key differences lie in their intended use, purity, and compliance standards.
If you are manufacturing supplements or skincare products for human use, please choose the food-grade version.
If you are conducting cell experiments or ingredient analysis, the research-grade version is preferred. Do not interchange them.
The choice depends primarily on your production line equipment and the final dosage form.
For soft capsules or skincare products, choose the 80% liquid concentrate.
For hard capsules or tablets, choose the 50% powder (this eliminates the solidification step, making the process the simplest).
Storage Conditions of Pantethine
- Pantethine should be stored in a sealed container, protected from light, and kept in a cool, dry environment; for long-term storage, refrigeration at a constant temperature of 2–8°C is recommended.
- Once opened, the material should be used promptly to prevent degradation or loss of efficacy due to prolonged exposure to air.
- The shelf life is 24 months under standard, unopened storage conditions.
Packaging Specifications of Pantethine
- Research Grade: Small, sealed, moisture-proof, and light-protected packages (100mg, 500mg, 1g, 5g, 10g).
- Food Grade: Standard packaging (25kg/drum).
- Customized packaging sizes available upon request.
Minimum Order Quantity (MOQ) & Pricing of Pantethine
- Research Grade: Small-quantity sample orders supported; no high minimum order thresholds; suitable for laboratory R&D and testing.
- Food Grade: Standard MOQ of 100kg; flexible order quantities supported; tiered pricing structure; exclusive discounts available for bulk purchases.
- Custom quotes available for all specifications; please contact us online for the latest price list.
Sample Service of Pantethine
Free raw material samples available for experimental testing and formulation evaluation; shipping costs are borne by the buyer; requests can be submitted online.
