Basic Information of O-Phospho-L-Serine
- Product Name: O-Phospho-L-serine
- English aliases: L-Serine O-phosphate, Phosphoserine, O-Phospho-L-serin, O-Phospho-L-serine, L-Serine phosphate, Phosphorylated L-serine, L-Serine O-phosphate， L-SOP
- Industry Abbreviations: L-PS, Phospho-L-serine
- Other language names: German: O-Phospho-L-serin; French: O-Phospho-L-sérine; Spanish: O-Fosfo-L-serina
- CAS number: 407-41-0
- Molecular Formula: C₃H₈NO₆P
- Molecular Weight: 185.07 g/mol
- Product Grade: Pharmaceutical grade, Food grade, Reagent grade, Cosmetic grade
- Main uses: Nutritional supplements, Food additives, Pharmaceutical intermediates, Cosmetic raw materials
Physicochemical Properties of O-Phospho-L-Serine
- Appearance and smell: White to off-white crystalline powder, odorless, slightly acidic taste.
- Solubility: Easily soluble in water (solubility approximately 30 g/100 mL at 25°C), slightly soluble in ethanol, and insoluble in ether and chloroform.
- Boiling Point: Decomposition (decomposition above 220℃)
- Melting Point: 175-180℃ (decomposes)
- Density: 1.68-1.72 g/cm³ (solid crystal density)
- Purity: ≥98% (pharmaceutical grade), optical purity ≥99%ee
- Stability: Store in a cool, dry place where it is stable, avoiding high temperatures, humidity, and light.
- Danger: Low toxicity or practically non-toxic; some products may cause slight irritation.
- Emergency Response: Skin contact: Rinse immediately with plenty of water; Ingestion: Seek immediate medical attention.
Supplementary Technical Details for O-Phospho-L-Serine
- Production Methods: L-serine is obtained by phosphorylation of phosphoric acid in the presence of a catalyst, followed by purification by ion exchange chromatography.
- Acute Toxicity (LD50): Oral LD50 in rats: >5000 mg/kg (practically non-toxic); Intraperitoneal LD50 in mice: 3000-3500 mg/kg
- Chronic Toxicity: No significant toxicity with long-term use, meets pharmaceutical-grade USP standards.
- Upstream and downstream products (raw materials): L-serine, phosphoric acid, catalyst
- Upstream and downstream products (downstream): Brain function improvement drugs, nutritional supplements, cosmetic raw materials, biological reagents
- Quality Standards: Compliant with USP, EP, and GB
- Detection Methods: HPLC, UV, IR, etc.
- Transportation Methods: Sea freight, air freight, and express delivery
- Payment Methods: T/T, L/C, Western Union, etc.
- Certification Status: ISO9001, GMP, kosher halal etc.
- Technical Support: Provide product application technical guidance and solutions
Packaging and Storage of O-Phospho-L-Serine
- Packaging: 25kg/fiber drum (lined with polyethylene bag), or according to customer requirements
- Storage: Store in a cool, dry, and well-ventilated warehouse; avoid direct sunlight and moisture
- Shelf Life: 24 months from the production date under proper storage conditions
- CAS number: 407-41-0
- Molecular Formula: C₃H₈NO₆P
- Molecular Weight: 185.07 g/mol
- Implementation Standards: Enterprise standards or USP/BP/EP/CP
- Precautions: Avoid storing with strong oxidizers, strong acids, or strong alkalis; wear protective equipment during operation.
- After-sales Service: Provides COA and MSDS; free returns and exchanges for quality issues; technical support.
Applications of O-Phospho-L-Serine
- Pharmaceutical-grade O-Phospho-L-Serine can be used as a core pharmaceutical raw material or excipient.It is primarily used for clinical nutritional support (mainly through intravenous nutritional solutions) and as an adjunct treatment for neurological diseases (such as Alzheimer’s disease and stroke).Furthermore, it has no significant toxic side effects and can be used long-term.
- Pharmaceutical-grade O-Phospho-L-Serine can be used for solubilizing poorly soluble drugs and in the research and development of peptide drugs.
- Reagent-grade O-Phospho-L-Serine is a laboratory tool used in mechanistic studies and model building.For example, it can be used as an additive in cell culture media, or as a calibration standard for amino acid analyzers.
- Food-grade O-Phospho-L-Serine can be used as a key ingredient in nutritional supplements or as a functional food additive.It helps improve memory, relieve mental fatigue, and enhance cognitive function.It can be added to products such as milk powder, functional beverages, and nutritional capsules.
- Cosmetic-grade O-Phospho-L-Serine can be used as an ingredient in high-end skincare formulations.It has the effects of repairing the skin barrier, reducing inflammation, providing antioxidant protection, and firming the skin.
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