What is Mupirocin?
Mupirocin powder, also known as pseudomonal acid, is a metabolite produced in the culture medium of Pseudomonas fluorescens. It is also the API of Bactroban. It was introduced to the market by GlaxoSmithKline in 1985 and approved for use and sale in my country in 1993. Its production technology is not only stable, but its application technology is also very mature. Mupirocin powder is used in ointments and other forms to treat bacterial skin infections caused by Gram-positive cocci. It inhibits bacterial protein synthesis, thereby preventing bacterial growth and reproduction, thereby killing the bacteria.
Can Mupirocin be used as a Healing Powder?
Mupirocin can be used as a wound healing powder. As an effective antibiotic for treating bacterial skin diseases, mupirocin not only quickly kills bacteria in the affected area but also stimulates skin growth factors, accelerating wound healing and providing an anti-inflammatory effect. However, mupirocin is not suitable for large body areas because, besides the potential for irritation, it can also lead to excessive mupirocin levels in the body, potentially causing bacteria to develop resistance to the drug.
Why choose Highassay?
Highassay is a core supplier of pharmaceutical raw materials with 15 years of experience. Our mupirocin powder is pharmaceutical-grade and complies with the European Pharmacopoeia, the United States Pharmacopoeia, and our company standards. Our mupirocin powder boasts a purity of up to 95%. We have a wide range of professional testing equipment, transportation channels, and dedicated research and after-sales personnel to provide you with the highest quality service, the best product quality, the most competitive pricing, and comprehensive after-sales support.
If you have any questions about processing Mupirocin, Highassay’s R&D team is here to help.
Application of Mupirocin
Highassay adheres to strict quality control (QC) to produce Mupirocin. Buy Mupirocin in bulk from us now to get competitive market prices.
Mupirocin powder can be used in the production of mupirocin ointment, which is primarily used to treat bacterial skin conditions such as impetigo, boils, and folliculitis. It can also be applied to postoperative wounds to prevent bacterial infection.
Mupirocin powder can be used in the production of mupirocin nasal spray. Directly applied to the nasal cavity, the spray can relieve nasal swelling and pain caused by Staphylococcus aureus.
Mupirocin powder can be used in the production of mupirocin oral preparations, which are marketed in capsules, chewable tablets, and granules to treat mild bacterial infections, offering a more convenient and rapid delivery.
Mupirocin powder can be used in the production of mupirocin injections and infusions, used to treat patients with severe bacterial infections. Direct administration into the body in liquid form allows for easier absorption and faster results.
Can Mupirocin be used Long-term?
Long-term use is not recommended and requires medical supervision. Mupirocin finished products manufactured from mupirocin are antibiotics. Excessive dosages and frequent use can easily lead to bacterial resistance. Therefore, you should use the medication within the prescribed timeframe. However, you should not stop taking the medication on your own after seeing results to prevent a recurrence of the disease.
Specification of Mupirocin
- Specification of Mupirocin
- Chemical Properties of Mupirocin
| Product Name | Mupirocin |
| Synonym | Pseudomonic acid A |
| Appearance | White to off white solid |
| CAS No. | 12650-69-0 |
| Molecular Weight | 500.62 |
| Molecular Formula | C26H44O9 |
| Preparation | Fermentation |
| Storage Conditions | Store in an airtight container,protected from light and store at 2-8℃ |
| Solubility | Slightly soluble in water. Soluble in acetone, anhydrous ethanol and dichloromethane |
| Product Name | Mupirocin |
| Melting Point | 77-78℃ |
| Boiling Point | 672℃ |
| Density | 1.183±0.06g/cm3 |
| Flash Point | >110°(230°F) |
| Specific Rotation | D20 -19.3° (c = 1 in methanol) |
| Solubility | H2O: 12 mg/mL, soluble |
| Acidity Coefficient | 4.78±0.10(Predicted) |
| Optical Rotation | [α]/D -15.7 to -20°, c = 1 in methanol |
| λmax | 222nm(EtOH)(lit.) |
The Relationship Between Mupirocin and Sinus Rinse Powders
Mupirocin ointment can be added to sinus rinses for nasal irriga-tions caused by Staphylococcus aureus strains. It can also be used to treat chronic sinus infections. It’s important to note that if your medication has exceeded its expiration date, please dispose of it properly to prevent environmental contamination and consult a doctor for a replacement.
The Relationship Between Mupirocin and Minocycline
Mupirocin and minocycline are both antibiotics used to treat bacterial infections. However, they differ in that mupirocin is for topical use only, while minocycline is taken orally. If your bacterial infection is more severe and your doctor prescribes it, taking both medications internally or topically can provide faster relief.
