Product Overview
- Product Name: Celecoxib
- CAS: 169590-42-5
- Molecular Formula: C₁₇H₁₄F₃N₃O₂S
- Molecular Weight: 381.38
- Drug Class: Selective COX-2 inhibitor
- Dosage Forms: Oral capsules, long-acting sustained-release formulations
What is Celecoxib？
Celecoxib is a non-steroidal anti-inflammatory drug (NSAID) and the active ingredient in oral anti-inflammatory and analgesic formulations.
Mechanism of action: Celecoxib primarily works by selectively inhibiting cyclooxygenase-2 (COX-2) in the body, thereby reducing prostaglandin synthesis to achieve anti-inflammatory and analgesic effects.
Why choose Highassay?
Highassay is a Chinese supplier of high-quality Celecoxib API. We maintain rigorous standards for raw materials throughout every stage—from R&D to production—and offer Celecoxib in both powder and granular forms to suit your specific processing requirements.
- Quality: Our Celecoxib API features high purity, strict impurity control, and stable crystal form, with minimal batch-to-batch variation, ensuring the quality of your finished products.
- Supply: Highassay offers flexible supply capabilities, accommodating everything from small-scale R&D to large-scale commercial production.
- Compliance: We provide the COA, MSDS, and impurity profile with our products; additionally, we have completed the US DMF filing, which helps accelerate your drug product registration process.
Specification of Celecoxib
- Specification of Celecoxib
| Test Item | Specification Requirement |
| Appearance | White to offwhite crystalline powder |
| Assay (HPLC) | ≥99.0% |
| Individual Impurity | ≤0.1% |
| Total Impurities | ≤0.5% |
| Genotoxic Impurities (Key Control) | Synthetic intermediates such as SHH, MAP are strictly controlled, limits comply with EU & US pharmacopoeia filing requirements |
| Water Content | ≤0.5% |
| Heavy Metals | ≤10 ppm |
| Melting Point | 157℃159℃ |
| Solubility in Organic Solvents | Freely soluble in methanol, ethanol and DMSO; solubility in DMSO ＞20 mg/mL |
| Aqueous Solubility | Practically insoluble in water, 7 mg/L at 25 ℃ |
| Residual Solvents | Complies with ICH Q3C (or USP/EP) requirements |
Yes, Celecoxib is a prescription-strength analgesic (painkiller) and anti-inflammatory API.
Yes, Celecoxib is a typical non-steroidal anti-inflammatory drug (NSAID).
Yes, they are essentially the same substance; Celecoxib is the name of the API, while Celebrex is the brand name.
Co‑administration is not recommended. Combined use does not enhance analgesic or anti‑inflammatory effects, but significantly raises risks of gastrointestinal injury, renal burden and cardiovascular adverse events.
Application of Celecoxib
- Used in the manufacture of Celecoxib capsules (50/100/200 mg)
- Used as a COX-2 inhibitor research reagent
Packaging and Storage of Celecoxib
- Storage: Store in a cool, dry place (15–30°C), protected from light and tightly sealed.
- Packaging: 25 kg fiber drums, or 1 kg/5 kg aluminum foil bags (lined with moisture-proof LDPE bags).
Celecoxib Minimum Order Quantity (MOQ)
- MOQ: 1 kg.
- Competitive pricing for bulk orders; please contact customer service directly for details.
