Basic information of Carboprost Tromethamine
CAS No.：58551-69-2
Formula：C25H47NO8
Molecular Weight：489.64
Chemical purity：≥99.0%
Melting Point: 95°C and 105°C.
Solubility: Freely soluble in water (2 mg/mL), soluble in DMSO (100 mg/mL) and ethanol
Synonym of Carboprost Tromethamine
- (15S)-15-methyl prostaglandin F2α tromethamine salt
- 7-(3α,5α-dihydroxy-2ß-[(3S)-3-hydroxy-3-methyl-trans-1-octenyl]-1αcyclopentyl]-cis-5-heptenoic acid compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol
- (15S)-9α,11α,15-trihydroxy-15-methylprosta-cis-5, trans-13-dienoic acid, tromethamine salt
- (15S)-15-methyl PGF2α-THAM
What is carboprost Tromethamine?
It is a synthetic 15-methyl analog of prostaglandin F2α. In its highly purified form, carboprost tromethamine is a white to slightly off-white crystalline powder.
It is primarily used to promote regular uterine contractions and significantly reduce postpartum bleeding. It is clinically used in obstetrics and gynecology to reduce postpartum hemorrhage.
What is carboprost tromethamine used for?
Carboprost tromethamine belongs to the PGF2α class of drugs. It contains a (15S)-15-methyl derivative of natural prostaglandin F2α. It can regulate intracellular free Ca2+ concentrations, promote intercellular connectivity of uterine smooth muscle cells, and directly act on contractile proteins in uterine smooth muscle. Its half-life is longer than other drugs, resulting in a long-lasting, stimulating effect on uterine smooth muscle. It also has strong biological activity, promoting platelet aggregation, thereby shortening the blood clotting process and achieving hemostasis within a short period of time. It is clinically used in obstetrics and gynecology to reduce postpartum hemorrhage.
What are the specifications and purity levels of your Carboprost tromethamine?
Highassay offers both lab-grade and GMP-grade versions. Purities range from 97%, 98%, and 99%. Lab-grade versions are fully utilized for domestic and international drug development. GMP grades support commercial production, and we can provide relevant registration documents.
Highassay is Carboprost Tromethamine Supplier
Highassay is one of the Carboprost tromethamine API manufacturers and suppliers in China, with cGMP and DMF documentation support.
If you have any questions about Carboprost tromethamine API, the Highassay team is always available to assist you. Please feel free to contact us.
Highassay offers both lab-grade and cGMP-grade versions, subject to your requirements.
Highassay has built a high-end prostaglandin series industrialization platform with strong market competitiveness and competitive pricing.
It’s generally one week, delivered by express delivery, such as FedEx.
Highassay maintains stable production of Carboprost tromethamine and maintains a large inventory.
Bulk purchases do offer discounts, but the discount varies depending on the quantity. Please contact our sales department for specific discounts.
It promotes platelet aggregation, thereby shortening the blood clotting process and achieving rapid hemostasis.
It is used in obstetrics and gynecology to reduce postpartum bleeding.
Side Effects of Carboprost Tromethamine
Carboprost tromethamine can also irritate the smooth muscle of the human gastrointestinal tract.
This effect may cause vomiting, diarrhea, or both.
Some patients may also experience a transient increase in body temperature.
Specification of Carboprost Tromethamine API
| Items | Standards |
| Appearance | a white to slightly off-white crystalline powder |
| Identification | HPLC IR |
| Solubility | Freely soluble in water (2 mg/mL), soluble in DMSO (100 mg/mL) and ethanol |
| Melt range | melts between 95° and 105° C, depending on the rate of heating |
| Assay (anhydrous and solvent free basis) | 99% min |
| Storage Conditions | Store in a dry, airtight container away from light and stored below -20°C. |
