Specifications of Captopril
Purity 98%-101.5% USP/EP/BP Grade
- Product Name: Captopril
- CAS No.: 62571-86-2
- Molecular Formula: C9H15NO3S
- Molecular Weight: 217.285
- Appearance: White to off-white crystalline powder with a garlic-like odor
- Assay: 98%-101.5% (HPLC)
- Solubility: Easily soluble in methanol, ethanol, and chloroform; soluble in water
- Standards: USP/BP/EP/CHP
- Storage: Store in a cool, dry place, protected from light and odors; keep away from acidic, alkaline, and pungent ingredients.
- Shelf Life: 24 months from the production date under proper storage conditions.
Why choose Highassay’s Captopril?
- Highassay has a stable supply of Captopril：As a producer and supplier of Captopril raw materials in China,We have our own production factory, a complete set of production equipment, and sales, research and development, and after-sales service teams.
- Highassay can provide you with comprehensive Captopril data and after-sales service.
- Highassay has its own complete logistics support system and long-term partnerships with professional third-party logistics teams.
- Highassay boasts superior product quality：Purity: 98%-101.5%; Captopril powder of corresponding purity can be provided according to your needs.
What is Highassay’s Captopril?
Highassay’s Captopril is an active pharmaceutical ingredient used to treat conditions such as high blood pressure and heart failure.
- If you are a large integrated generic drug company, Highassay has stable production capacity, a good reputation and the ability to withstand risks, which can ensure a long-term stable supply of Captopril.
- If you are a small to medium-sized/specialty pharmaceutical company, Highassay offers great flexibility in terms of delivery time, minimum order quantity, and customized services.
If you need to purchase captopril raw materials, please contact us!
Highassay’s Captopril Quality Control
As a leading global supplier of Captopril raw materials, we have a complete quality testing process for our products.
- We rigorously test each batch of raw materials before warehousing, and maintain comprehensive dynamic monitoring of the entire production process.
- After each batch is completed, corresponding Captopril testing is conducted, including testing for Captopril purity and impurity content. A paper report is generated and shipped with the product packaging.
- Finally, before shipment, we conduct a final inspection of the product packaging to ensure the quality of the Captopril.
Packaging of Captopril
- For Captopril raw materials used in samples and reagents, we offer vials, suitable for measurement in milligrams or grams.
- For smaller quantities of Captopril raw materials: we can provide 500g or 1kg aluminum foil bags.
- For medium quantities of Captopril raw materials: we can provide 5kg or 10kg Captopril raw materials, mostly in aluminum cans.
- For larger quantities: we can also provide 25kg/fiber drums (lined with polyethylene bags).
- Or, to reduce unnecessary waste of Captopril raw materials, we can also provide other packaging according to your requirements.
Applications of Captopril
Highassay’s Captopril raw material has the advantages of high quality and high purity, which is not only crucial in the pharmaceutical field, but also has certain application value in the scientific research field, providing a foundation for the research of drugs and diseases in related fields.
Captopril has significant effects in treating diseases such as hypertension and heart failure.Captopril raw material can be used to produce a variety of oral formulations, such as captopril tablets, captopril extended-release tablets, and captopril capsules.
Captopril raw material also offers potential research directions for alleviating Parkinson’s disease:
- Captopril has antioxidant and anti-inflammatory effects, and can protect dopamine neurons in the brain.
- Captopril can, to some extent, reduce the severity of motor disorders induced by levodopa, and shows promise as an adjunct treatment for Parkinson’s disease.
Certificate of Captopril’s Analysis
- Certificate of Captopril’s Analysis
- Captopril’s Data
| Items | Standard |
| Appearance | White or off –white powder |
| Identification | IR spectrum conforms to the standard |
| Melting range | 104-110℃ |
| Specific rotation | -125 ~ -134° |
| Loss on drying | <1% |
| Residue on ignition | <0.2% |
| Heavy metals | <0.003% |
| Organic Volatile Important | Meets the requirements |
| Assay | 97.5%-102% |
| AMPA | <0.2% |
| Captopril disulfide | <10% |
| Single unknown impurity | <0.2% |
| Total unknown impurities | <0.5% |
| Conclusion | Comply with USP28/BP2003 |
- Captopril’s Certificate of Analysis
- Captopril’s Gluten-Free Certificate
- Captopril’s GMP Certificate
- Captopril’s Safety Data Sheet (SDS)
- Captopril’s Methods of Analysis (MOA)
- Captopril’s Particle size data (PSD)
- Packaging conditions – Storage and transport conditions for the raw material
- List of transport requirements. For cold chain materials, monitoring procedure and report of measurement data to the laboratory.
- For substances that are mixtures or processed, the qualitative and quantitative formula.
The price of Captopril powder is based on its purity; different purities of Captopril have different prices. If you are interested in our products, please contact me and I will provide you with a corresponding product quote as soon as possible.
Captopril is soluble in water; at 25°C,and its solubility in water is 160 mg/ml.
Captopril raw materials are generally supplied to B2B manufacturers of Captopril drugs. Whether you are a large-scale Captopril formulation production plant or a small to medium-sized Captopril manufacturer, Highassay is willing to become your long-term partner.
Captopril can also be used in disease, experimental, and drug research. If you are a laboratory, research institute, or other research facility, you can also choose our Captopril raw materials.
Mechanism of Action of Captopril
Captopril lowers blood pressure by inhibiting the ACE enzyme in the body.
Advantages of Captopril
Captopril protects the heart and kidneys while lowering blood pressure, making it particularly suitable for patients with high blood pressure who also have diabetes, heart failure, or chronic kidney disease.
Captopril VS Lisinopril
Both Captopril and Lisinopril are ACEI inhibitors and they share the same mechanism of action.
The biggest difference between Captopril and Lisinopril lies in their metabolic pathways and duration of action in the human body.
Captopril is a first-generation drug that has a rapid onset of action but a short duration of action. It needs to be taken 2-3 times a day and is more suitable for certain hypertensive emergencies.Lisinopril is a third-generation drug with a relatively slow onset of action but a long duration of action. It only needs to be taken once a day, making it a better choice for long-term control of blood pressure and treatment of heart failure.
Captopril contains thiol groups, which carries a higher risk of causing rashes and taste disturbances; while lisinopeptide does not contain thiol groups and is a derivative of lysine, with fewer related side effects.
Captopril needs to be taken on an empty stomach and needs to be metabolized by the liver to be fully effective;Lisinopril is not affected by diet and is best taken at the same time every day. It does not need to be metabolized by the liver and can be excreted directly in its original form through the kidneys.
