Cosmetic Grade Azelaic Acid Raw Material (CAS 123-99-9) Bulk Wholesale
- Highassay offers various types of Cosmetic-grade Azelaic Acid raw materials, including Unencapsulated Azelaic Acid powder, Cyclodextrin-encapsulated Azelaic Acid, and a 10% Pre-dispersed Azelaic Acid suspension.
- We support bulk supply, customized particle sizes, custom packaging, and R&D sample services.
- Every batch comes with a complete Certificate of Analysis (COA), Material Safety Data Sheet (MSDS), and batch test report.
- These raw materials meet cosmetic formulation standards and serve as active ingredients for treating acne, soothing redness, and improving post-inflammatory hyperpigmentation.
Cosmetic-grade Azelaic Acid Powder
This is the most fundamental and widely used Cosmetic-grade form of Azelaic Acid on the market. We utilize a micronization process to grind the crystals into a fine powder, which helps improve the skin feel of your final product. At room temperature, this raw material is sparingly soluble in both water and oil, making it suitable for high-concentration formulations such as suspension gels and creams.
Product Advantages:
We offer customized micronization services tailored to specific formulation requirements and provide comprehensive microbiological test data to ensure compliance for cosmetic raw materials.
With ample stock and flexible minimum order quantity (MOQ), we offer significant cost advantages that help you manage mass production expenses.
Product (Raw Material) Efficacy:
- Inhibits Cutibacterium acnesand provides anti-inflammatory effects, helping to alleviate inflammatory acne and skin redness.
- Inhibits tyrosinase and selectively targets abnormal melanocytes, thereby fading acne marks and post-inflammatory hyperpigmentation.
- Regulates follicular keratinization and unclogs pores, contributing to improved skin condition.
Formulation Recommendation:
Standard Cosmetic-grade Azelaic Acid powder is suitable for High-concentration Azelaic Acid products, such as azelaic acid creams, anti-acne gels, and oil-control skincare products.
Cyclodextrin inclusion complex of Azelaic Acid
This is a supramolecular technology that utilizes the cavity structure of cyclodextrin to Encapsulate Azelaic Acid molecules, thereby overcoming the challenges of poor water solubility and high irritation associated with Azelaic Acid. It is suitable for high-end custom formulations, enabling the creation of transparent products with low active ingredient concentrations.
Product Advantages:
Compared to standard, Non-encapsulated Azelaic Acid raw materials, this Encapsulated version offers significantly improved water solubility, enhanced stability, and reduced irritation. It also features a sustained-release effect, prolonging the duration of its efficacy.
We provide reliable, verified active content specifications and offer professional formulation guidance for creating gentle skincare products with low inclusion levels.
Key Specifications:
- Active Azelaic Acid Content: 40%–45%
- Solubility: ≥5%
- Solid Content: 90%–100%
- Loss on Drying: ≤10.0%
- Heavy Metal Content: ≤10 ppm
- pH (5% solution): ≤5.5
Formulation Recommendations:
This ingredient is suitable for clear serums, aqueous solutions, low-inclusion formulas for redness reduction, high-end medical-grade skincare products, and more.
10% Azelaic Acid Suspension
This is a pre-dispersed suspension designed specifically for cosmetic manufacturing facilities. We have uniformly dispersed azelaic acid powder into a liquid phase system through milling, thereby eliminating issues such as airborne dust and uneven dispersion during production.
Product Advantages:
We supply pre-dispersed azelaic acid raw material, helping your facility save on production equipment, labor, and time costs.
The material is uniformly dispersed and free of agglomeration in every batch, allowing for direct addition and use.
Usage Recommendations:
Formulators or manufacturers can directly combine this product with humectants, preservatives, pH adjusters, and thickeners for further processing; the final formulation is then subjected to stability testing before being filled into creams or serums.
Unencapsulated vs Encapsulated Azelaic Acid
Item | Unencapsulated Azelaic Acid Powder | Cyclodextrin-encapsulated Azelaic Acid |
| Structure | Pure Azelaic acid crystal, no carrier | Azelaic acid encapsulated by cyclodextrin carrier |
| Water Solubility | Very poor, only 0.24% at 25℃ | Greatly improved, supports high-concentration water solubility |
| Formula Forms | Suitable for suspension creams/gels; difficult to produce clear aqueous formulations | Can be formulated into transparent essences, aqueous solutions and cleansers |
| Irritation | Raw acid contacts epidermis directly; higher irritation at high concentrations | Sustained release, milder at the same concentration |
| Transdermal Release | Immediate effect upon skin contact, fast release | Slow and sustained release, longer acting time |
| Cost | Low cost, sufficient stock, mainstream bulk material | Significantly higher raw material unit price |
| COA Annotation | Test for the content of pure Azelaic Acid | Test for available Azelaic Acid loading in the inclusion complex |
No. It must first undergo preservative efficacy testing, microbiological testing, stability testing, and regulatory filing; otherwise, it cannot be marketed as a finished cosmetic product.
Because the actual Azelaic Acid content in the inclusion complex is very low; achieving a high concentration would require introducing a large amount of Cyclodextrin. This compromises the formula regarding the active ingredient ratio, skin feel, and stability. Furthermore, the cost of this raw material is significantly higher than that of standard Azelaic Acid.
Yes, Azelaic Acid can improve acne conditions through multiple mechanisms. It is frequently used in various types of anti-acne product formulations.
They can be used in an alternating regimen: tretinoin targets closed comedones and fine lines, while azelaic acid suppresses redness and inflammatory acne marks. However, layering them on the same day is not recommended, as the risk of irritation increases significantly.
No, Azelaic Acid is not a traditional exfoliating agent that causes skin peeling. It improves the skin primarily through antibacterial, anti-inflammatory, and keratinization-regulating effects, rather than by physical or chemical exfoliation.
Yes. However, the risk of irritation may be additive, so formulators should conduct tolerance testing; combining high concentrations of both in a single product is not recommended for sensitive skin.
