Product Overview
- Product Name：Acetaminophen(Paracetamol)
- Chemical name：N-(4-Hydroxyphenyl)acetamide
- CAS No.：103-90-2
- Molecular Formula：C₈H₉NO₂
- Molecular Weight：17
- Usage：Pharmaceutical API
What is Acetaminophen?
Acetaminophen (also known as Paracetamol) is a common antipyretic-analgesic active pharmaceutical ingredient (API) belonging to the acetanilide class.
Mechanism of Action: It primarily acts centrally by inhibiting prostaglandin synthesis in the hypothalamic thermoregulatory center, thereby exerting an antipyretic effect; it also provides analgesia by raising the pain threshold.
We supply pharmaceutical-grade Acetaminophen API that meets USP, BP, EP, and CP pharmacopeial standards, suitable for the formulation of various antipyretic-analgesic products, including tablets, capsules, oral solutions, and granules.
Why choose Highassay?
We supply high-purity Acetaminophen API with a purity of ≥99.5% and a key impurity (p-aminophenol) level below 10 ppm. This ensures the safety and stability of your formulations, helping you easily pass regulatory reviews.
- Process Advantages:We utilize an advanced one-step synthesis process that streamlines production and achieves a yield of over 95%. Heavy metal residues are strictly controlled to meet pharmacopoeia limits, making the product ideal for formulations intended for children and sensitive populations.
- Reliable Supply: We maintain year-round stock to ensure uninterrupted production. Packaging options range from 15 kg to 100 kg, and we support OEM repackaging to meet your specific production needs.
- Comprehensive Support:We provide free COAs, MSDS, and samples, and support small-batch trial orders (starting at 100 kg) to help you complete product development efficiently.
Specification of Acetaminophen
- Specification of Acetaminophen
Test Item | Specification |
| Appearance | White crystalline powder or crystalline solid |
| Assay | ≥99.5% |
| Melting Point | 168 ~ 172℃ |
| Water Content | ≤0.5% |
| Residue on Ignition | ≤0.1% |
| Heavy Metals | ≤0.002% |
| Chloride | ≤0.014% |
| Sulphate | ≤0.02% |
Tylenol is one well-known commercial brand.
Antipyretic (fever-reducing): Used for fevers caused by the common cold or influenza; it is one of the most widely used fever-reducing medications.
Analgesic (pain-relieving): Used to alleviate mild to moderate pain, including headaches, toothaches, neuralgia, joint pain, and menstrual cramps.
It typically has a shelf life of three years when stored under recommended conditions and kept unopened.
Solid oral dosage forms, liquid oral dosage forms, granules/dry suspensions, and suppositories.
The API supplied by Highassay features high purity and low impurity levels, making it suitable for the production of all the aforementioned dosage forms.
Because the highly oxidative environment within inflamed tissues inactivates the drug, preventing it from effectively inhibiting peripheral prostaglandin synthesis; consequently, it is not very effective for treating inflammatory conditions such as arthritis.
Applications of Acetaminophen API
- For oral tablet/capsule preparation
- For pediatric antipyretic formula
- For compound analgesic API blending
- For fever-pain relief formulations related to ear discomfort
Storage and Packaging
- Storage:Paracetamol API should be stored in a cool, dry place, protected from light and tightly sealed.
- Packaging:15 kg, 25 kg, 80 kg, or 100 kg per fiber drum. Packaging can be customized to meet your requirements and facilitate production.
Minimum Order Quantity (MOQ)
- Standard MOQ is 1000 kg.
- We offer flexible order quantities and tiered pricing based on purchase volume.
- Small trial orders are acceptable for new product development. Bulk orders enjoy competitive volume discounts.
- Please contact us for the latest quotation.
Sample Service
We offer a channel for requesting free samples; please contact us online if you wish to make a request.
