Highassay's Bicalutamide Overview
- CAS Number: 90357-06-5
- Molecular Formula: C₁₈H₁₄F₄N₂O₄S
- Molecular Weight: 430.37
- INN Name: Bicalutamide
- EINECS Number: 618-534-3
- Drug Class: Non-steroidal anti-androgen
Why choose Highassay's Bicalutamide?
Highassay supplies high-purity (≥99%), pharmaceutical-grade Bicalutamide (CAS: 90357-06-5) that meets CP, USP, and EP pharmacopoeia standards.
We support orders ranging from small-scale samples (gram level) to commercial production (kilogram level); shipments include a Certificate of Analysis (COA) and a Material Safety Data Sheet (MSDS).
Bicalutamide Packaging
Standard packaging: 1 kg, 5 kg, and 25 kg specifications (fiber drums with double-layer pharmaceutical-grade polyethylene liners).
Special packaging: Customized packaging services are available to meet your specific needs and enhance convenience.
All packaging materials meet pharmaceutical-grade standards, ensuring the product remains uncontaminated during storage and transportation.
Bicalutamide Storage
Store in a sealed container, protected from light, in a dry place; recommended storage temperature is below 25°C. Under these conditions, the shelf life is 36 months.
Bicalutamide MOQ
Flexible minimum order quantities (MOQ) can be arranged based on your specific requirements; please contact us online to discuss.
Bicalutamide Pricing
We utilize a tiered pricing model: the larger the order volume, the more favorable the price.
Buy high-quality Bicalutamide API,choose Highassay.
Application of Bicalutamide
Highassay’s Bicalutamide serves as the core raw material for the manufacture of Bicalutamide tablets and capsules.
Bicalutamide Tablets: Typically available in 50 mg and 150 mg dosages.
Bicalutamide Capsules: Most commonly available in 50 mg capsules.
What is Bicalutamide?
Bicalutamide, a non-steroidal anti-androgen, is primarily used in combination with medical or surgical castration to treat advanced prostate cancer.
Mechanism of action of Bicalutamide: It competitively binds to androgen receptors on prostate cancer cells, blocks stimulation by testosterone and dihydrotestosterone, inhibits tumor growth, and induces apoptosis.
As a more commonly used first-line clinical choice, bicalutamide offers potent and sustained anti-androgenic effects, with the added advantage of a mild side-effect profile.
Specification of Bicalutamide
- Specification of Bicalutamide
| Item | Specification |
| Appearance | White or almost white crystalline powder |
| Assay (on dried basis) | 98.0% ~ 102.0% |
| Purity (HPLC) | ≥ 99.0% |
| Single impurity | ≤ 0.5% |
| Total impurities | ≤ 1.0% |
| Water | ≤ 0.5% |
| Sulfated ash / Residue on ignition | ≤ 0.1% |
| Heavy metals | ≤ 20 ppm (≤ 0.002%) |
| Melting point | 193 ~ 196 ℃ (Melting range ≤ 2 ℃) |
| Solubility | Freely soluble in tetrahydrofuran, acetone, DMF;Sparingly soluble in methanol;Slightly soluble in ethanol;Practically insoluble in water |
Bicalutamide is used as an antiandrogen agent to block the binding of androgens to the androgen receptor (AR) in prostate cancer cells.
No, it is not a chemotherapy drug; rather, it is a hormonal therapy medication.
It can be used as a monotherapy or in combination with surgical or medical castration (such as gonadotropin-releasing hormone agonists) to treat advanced prostate cancer; this combination approach is known as “maximal androgen blockade.”
Answer: Bicalutamide is the preferred choice for prostate cancer treatment as it is a highly specific and potent antiandrogen. Spironolactone has weak antiandrogenic activity and carries risks of hormone-related side effects; it is used primarily as a diuretic and is not part of the standard treatment regimen for prostate cancer.
