Basic Information of PQQ
- Product Name: Pyrroloquinoline Quinone
- Synonyms: PQQ, Methoxatin, Pyrroloquinoline quinone disodium salt, Methoxatin disodium salt
- CAS No.: 122628-50-6
- Molecular Formula: C14H4N2Na2O8
- Molecular Weight: 374.17
- Category: Aromatic ortho-quinone compound
Applications of PQQ
- PQQ Supplement(The Largest Application Market for PQQ)—–As a main ingredient,Widely used in dietary supplement formulations targeting mitochondrial health, brain health, anti-fatigue effects, and more.
- Functional Foods—–Added PQQ into energy drinks, meal replacement powders, nutritional foods for middle-aged and elderly people, etc.
- Cosmetic—–Added PQQ as an auxiliary ingredient to topical anti-aging products.Leverages its antioxidant and skin-repairing properties.
Why choose Highassay?
Highassay is a China-based supplier of PQQ raw materials. We offer food-grade, cosmetic-grade, and pharmaceutical-grade PQQ powder, with our food-grade PQQ serving as our flagship product.
Purity Advantage
Our PQQ raw material has a purity of ≥99%, is free of impurities and harmful residues, and complies with FDA standards.
Production Process
We use the mainstream microbial fermentation method currently available on the market for production.We possess mature technology and achieve large-scale production.
Complete documentation
We provide you with COAs, MSDSs, heavy metal and microbial testing data.To ensure that the PQQ disodium salt you purchase meets food-grade or pharmaceutical-grade requirements.
Application Advantages
Our PQQ powder has good water solubility and strong stability, and we also offer customized PQQ raw material services (purity, specifications). It can be used in many areas, including dietary supplements, functional foods, and cosmetics.
For bulk purchases of PQQ powder, choose Highassay. Place your order now to enjoy special discounts; click below to inquire for details.
PQQ : Packaging and Storage
Packaging of PQQ
We offer two standard packaging options: aluminum foil bags or cardboard drums. If you have any custom packaging requirements, please inform us in advance.
Aluminum Foil Bags: ≤5 kg; suitable for samples, R&D prototyping, and small-batch production.
Cardboard Drums: 25 kg per drum; primarily used for large-scale industrial production.
Storage of PQQ
Store in a cool, dry and ventilated place, keep away from light, moisture and peculiar smell. Keep container tightly sealed when not in use. Refrigeration is recommended for long-term storage.
Specification of PQQ
- Specification of PQQ
- Comparison of Three PQQ Production Processes
- Comparison of PQQ Forms
| Item | Specification |
| Appearance | Reddish brown to dark reddish brown powder |
| Melting Point | >300°C (decomposes) |
| Solubility | Freely soluble in water; solubility in water approx. 6.16 mg/mL |
| Bulk Density | 0.5 – 0.7 g/cm³ |
| pH Value (1% aqueous solution) | Approx. 6.0 – 8.0 |
| Loss on Drying / Water Content | ≤ 12.0% |
| Heavy Metals | ≤ 10 ppm (Pb, As, Hg, Cd ≤ 0.5 mg/kg each) |
| Assay | ≥ 99.0% (on dry basis, determined by HPLC) |
| Single Impurity | ≤ 1.0% (subject to actual COA) |
| Total Impurities | ≤ 2.0% (subject to actual COA) |
| Item | Natural Extraction | Chemical Synthesis | Microbial Fermentation |
| Technical Maturity | Laboratory only | Mature industrial scale | Mature industrial scale |
| Cost | Extremely high | Relatively low | Medium (continuously decreasing) |
| Environmental Impact | Excellent | Poor (high pollution) | Excellent |
| Production Capacity | Not feasible | Large | Large |
| Consumer Acceptance | High | Medium (labeled as “synthetic”) | High (labeled as “bio-fermented”) |
| Purity Standard | — | ≥99% (specific impurities tested) | ≥99% (microbial indicators tested) |
| Item | PQQ (Free Acid) | PQQ Disodium Salt |
| CAS No. | 72909-34-3 | 122628-50-6 |
| Molecular Weight | 330.21 | 374.17 |
| Water Solubility | Low | High (~6.16 mg/mL) |
| Stability | Moderate | More stable, ideal for commercial formulations |
| Regulatory Status | For research use only | Approved as new food raw material, applicable in food products |
| Commercial Applications | Reference material / standard | Dietary supplements, functional foods, beverages |
We offer flexible MOQs. You are welcome to contact us to discuss and negotiate the MOQ; we will provide recommendations tailored to your specific purchasing volume.
For small-batch orders, we maintain stock and will ship immediately upon receipt of payment; for large-batch orders, we will ship within 7 days.
The relationship between PQQ, NMN, and CoQ10 is not competitive, but rather complementary and synergistic. These three compounds target different stages of mitochondrial health; when used in combination, they form a more comprehensive anti-aging regimen.
Breast milk, natto, parsley, green tea, green peppers, and kiwis are all natural sources of PQQ; among these, breast milk contains the highest concentration, followed by natto. However, the levels found in food are extremely low—insufficient to meet our daily requirements.
The most common PQQ supplements available on the market come in four dosage forms: capsules, tablets, powders, and liquid beverages; among these, capsules are the most prevalent.
What is PQQ?
PQQ is a small molecule quinone redox coenzyme. High-purity PQQ is commercially available as PQQ disodium salt.Compared to unstable free acids, the disodium salt form has superior stability and solubility.It is the gold standard in commercial formulations.
As the core ingredient in PQQ nutritional supplements, the quality of the PQQ itself determines the overall quality of the supplement.
For your PQQ raw material needs, choose Highassay. Contact us today, and we will provide you with the latest quotation for PQQ raw materials within 24 hours. To request a free sample, please contact our customer service team, and we will arrange it as soon as possible.
Sources of PQQ
PQQ exists naturally in bacteria, plants, and animals; We cannot produce it on our own.The PQQ in our bodies is primarily derived from our diet, yet its content in food is extremely low.So we need to rely on PQQ supplements to meet the daily dosage requirement of 10–20 mg.
PQQ raw material can be produced by three main methods: natural extraction, chemical synthesis, and microbial fermentation. comparison of them can be found in the table above.
Mechanism of Action of PQQ
Mitochondria are the energy factories of the cell; PQQ energizes cells and promotes their health by stimulating new mitochondria growth.Strong antioxidant properties to protect existing mitochondria from oxidative stress.These features give it a distinctive role in anti-aging, neuroprotection, and metabolic regulation.
