Product Overview
- Product Name: Bupivacaine
- CAS No.: 2180-92-9/14252-80-3, 73360-54-0
- Molecular Formula: C₁₈H₂₈N₂O/C₁₈H₂₈N₂O·HCl, C₁₈H₂₈N₂O·HCl·H₂O
- Molecular Weight: 288.43/324.89, 342.90
- Appearance: White crystalline powder
- Drug Class: Amide-type local anesthetic
Specification of Bupivacaine
| Item | Bupivacaine (2180-92-9) | Bupivacaine Hydrochloride (14252-80-3) |
| Molecular Formula | C₁₈H₂₈N₂O | C₁₈H₂₈N₂O·HCl |
| Molecular Weight | 288.43 | 324.89 |
| Assay (on dried basis) | ≥99.0% | ≥99.0% |
| Single Impurity | ≤0.5% | ≤0.5% |
| Total Impurities | ≤2.0% | ≤2.0% |
| Moisture | ≤0.5% | ≤0.5% (Anhydrous) / ≤5.0% (Monohydrate) |
| Melting Point | 107.5–108°C | 105–107°C |
| pH Value (1% aqueous solution) | 4.5–6.0 | 4.0–6.5 |
| Solubility | Freely soluble in ethanol, soluble in water | Freely soluble in water (Essential for injections) |
The standard MOQ is 1 kg; we accept small-batch trial orders, and pricing for large volumes is negotiable.
Highassay can provide 10–50g samples (freight collect) for quality testing and formulation development; please contact us for details.
Our products come with full export qualifications. We can provide documents such as MSDS, COA, and export licenses to facilitate customs clearance worldwide.
Highassay’s Bupivacaine
Highassay offers Bupivacaine (CAS: 2180-92-9) and Bupivacaine Hydrochloride (CAS: 73360-54-0/14252-80-3) as active pharmaceutical ingredients (APIs). These products feature high purity, comply with EP/USP/CP standards, and are highly water-soluble, making them suitable for the R&D and production of injectable formulations. They are available from stock, with COA and MSDS provided.
| Item | Bupivacaine (Base) | Bupivacaine HCl (Mainstream) |
| CAS No. | 2180-92-9 | 14252-80-3 (Anhydrous) / 73360-54-0 (Monohydrate) |
| Grade | Pharmaceutical grade | Pharmaceutical grade (EP / USP / CP) |
| Appearance | White crystalline powder | White crystalline powder |
| Purity | ≥99.0% | ≥99.0% |
| Solubility | Freely soluble in ethanol, soluble in water | Freely soluble in water (Key advantage for injections) |
What is Bupivacaine?
Bupivacaine (CAS No. 2180-92-9): An amide-type, long-acting local anesthetic (base form) primarily used by pharmaceutical companies for the R&D and manufacture of finished products; it serves as a synthetic precursor for bupivacaine hydrochloride or as a raw material for specialized formulations.
Bupivacaine Hydrochloride (CAS No. 14252-80-3/73360-54-0): The salt form of bupivacaine that is most common in the market and widely used in clinical practice; due to its excellent water solubility, it is a key raw material for producing formulations such as injections and nerve block agents.
Bupivacaine Packaging
- Small packaging: 1 kg / aluminum foil bag (with PE inner liner)
- Large packaging: 25 kg / fiber drum (with double-layer PE inner liners)
- Customization: Specifications such as 5 kg or 10 kg are available upon request.
Bupivacaine Storage and Transport
- Storage conditions: Store in a sealed container in a cool, dry place; protect from light.
- Shelf life: 36 months (unopened).
- Transport: Not classified as a hazardous chemical; transport as general chemical goods.
