Basic Information of Riboflavin Sodium Phosphate Dihydrate
- Product Name: Riboflavin Sodium Phosphate Dihydrate
- English aliases: Riboflavin 5′-monophosphate sodium salt dihydrate, Vitamin B2 sodium phosphate dihydrate, FMN sodium salt dihydrate, Riboflavin Sodium Phosphate, Vitamin B2 phosphate, Riboflavin sodium salt, Riboflavin phosphate dihydrate
- Industry Abbreviations: FMN-Na·2H₂O, VB2-NA
- Other language names: German: Riboflavin-Natriumphosphat-Dihydrat; French: Riboflavine phosphate de sodium dihydraté; Spanish: Riboflavine phosphate de sodium dihydraté
- CAS number: 6184-17-4
- Molecular Formula: C17H24N4NaO10P
- Molecular Weight: 498.36 g/mol
- Product Grade: Pharmaceutical grade, Food grade, Industrial grade, Cosmetic grade
- Main uses: Nutritional supplements, Food additives, Pharmaceutical intermediates, Cosmetic raw materials
Physicochemical Properties of Riboflavin Sodium Phosphate Dihydrate
- Appearance and smell: Orange-yellow crystalline powder, odorless, slightly bitter taste.
- Solubility: Easily soluble in water (solubility approximately 20 g/100 mL at 25°C), slightly soluble in ethanol, and insoluble in ether and chloroform.
- Boiling Point: Decomposition (decomposition above 250℃)
- Melting Point: 230-235℃ (decomposes)
- Density: 1.58-1.62 g/cm³ (solid crystal density)
- Purity: ≥98% (Pharmaceutical Grade)
- Stability: Store in a cool, dry place where it is stable, avoiding high temperatures, humidity, and light.
- Danger: Low toxicity or practically non-toxic; some products may cause slight irritation.
- Emergency Response: Skin contact: Rinse immediately with plenty of water; Ingestion: Seek immediate medical attention.

Supplementary Technical Details for Riboflavin Sodium Phosphate Dihydrate
- Production Methods: Riboflavin is phosphorylated to form riboflavin phosphate, which then reacts with sodium hydroxide to form a salt, and crystallization yields a dihydrate.
- Acute Toxicity (LD50): Oral LD50 in rats: >5000 mg/kg (practically non-toxic); Intraperitoneal LD50 in mice: 3000-3500 mg/kg
- Chronic Toxicity: No significant cumulative toxicity with long-term use, meets pharmaceutical-grade USP and EP standards.
- Upstream and downstream products (raw materials): Riboflavin, phosphoric acid, sodium hydroxide, purified water
- Upstream and downstream products (downstream): Vitamin B2 injection, oral liquid, food additive, cosmetic raw material
- Quality Standards: Compliant with USP, EP, and GB
- Detection Methods: HPLC, UV, IR, etc.
- Transportation Methods: Sea freight, air freight, and express delivery
- Payment Methods: T/T, L/C, Western Union, etc.
- Certification Status: ISO9001, GMP, kosher halal etc.
- Technical Support: Provide product application technical guidance and solutions
Packaging and Storage of Riboflavin Sodium Phosphate Dihydrate
- Packaging: 25kg/fiber drum (lined with polyethylene bag), or according to customer requirements
- Storage: Store in a cool, dry, and well-ventilated warehouse; avoid direct sunlight and moisture
- Shelf Life: 24 months from the production date under proper storage conditions
- CAS number: 6184-17-4
- Molecular Formula: C₁₇H₂₀N₄NaO₉P·2H₂O
- Molecular Weight: 514.36 g/mol
- Implementation Standards: Enterprise standards or USP/BP/EP/CP
- Precautions: Avoid storing with strong oxidizers, strong acids, or strong alkalis; wear protective equipment during operation.
- After-sales Service: Provides COA and MSDS; free returns and exchanges for quality issues; technical support.

Applications of Riboflavin Sodium Phosphate Dihydrate
- Food-grade Riboflavin Sodium Phosphate Dihydrate is the active form of vitamin B2 and a core ingredient in nutritional supplements.It can be used in dietary supplements, and can also be added to cereals and cereal products, dairy products and their alternatives, beverages, and foods for special dietary uses.It helps prevent vitamin B2 deficiency and safeguards human health.
- Food-grade Riboflavin Sodium Phosphate Dihydrate can be used as a functional food additive.Riboflavin sodium phosphate itself has a bright yellow color, is safe and stable, and is one of the natural coloring agents;It also serves as an antioxidant additive in food, helping to improve product stability and quality.
- Feed-grade Riboflavin Sodium Phosphate Dihydrate can be added to animal feed as a feed additive.It can effectively supplement the vitamin B2 required by animals, promoting growth, improving feed conversion rate, and enhancing reproductive performance.
- Pharmaceutical-grade Riboflavin Sodium Phosphate Dihydrate is a core active pharmaceutical ingredient used in injectable and oral formulations.It is the preferred treatment for clinical vitamin B2 deficiency (cheilitis, glossitis, keratitis, etc.) and can also be used as an adjunct therapy for various other diseases.
- Reagent-grade Riboflavin Sodium Phosphate Dihydrate can be used as a common reagent/standard in biochemical, cell biological, and pharmacological research.
- Cosmetic-grade Riboflavin Sodium Phosphate Dihydrate can be added in small amounts to skincare products to help promote skin metabolism and improve skin problems associated with seborrheic dermatitis.
- Industrial-grade Riboflavin Sodium Phosphate Dihydrate is an intermediate for the synthesis of other riboflavin derivatives and can also be used as an industrial colorant and a weak antioxidant.
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