A Brief Introduction to Apigenin
Molecular Formula:C15H10O5
Molecular Weight:270.237
CAS No.:520-36-5
Appearance:Yellow to pale yellow powder
Regular commercial package:25kg/drum
What is Apigenin?
- Apigenin is a naturally occurring flavonoid compound with various biological activities, found in many plants,such as celery leaves, chamomile, and citrus fruits.
- Chamomile (especially German chamomile) is one of the plants rich in Apigenin and is known as an “ancient medicinal herb.” It has soothing, calming, anti-inflammatory, and antioxidant effects, largely due to the presence of A Apigenin extracted from chamomile is sometimes referred to as chamomile Apigenin.
- Apigenin has very low solubility in water, which limits its applications to some extent. However, as a dietary component, its long-term cumulative effects and local effects on the gastrointestinal tract remain important.
Highassay’s Apigenin
Highassay offers Apigenin raw materials with a purity of 98% or higher. Our Apigenin raw materials are yellow to pale yellow powders.Furthermore, 98% of the active ingredient in Highassay’s Apigenin was detected using the HPLC method.High-purity Apigenin powder is hygroscopic. We will ensure the quality and stability of the raw material through strict packaging and comprehensive quality control.Complete product documentation for Apigenin is provided with the product, including safety data sheets, certificates of origin, and method validation reports.
Our Apigenin raw materials are pharmaceutical-grade products and can be used in the production and processing of functional foods, pharmaceuticals, and cosmetics.
For purchasing Apigenin raw materials, choose Highassay!
Applications of Apigenin-----Daily Necessities
Added as an auxiliary ingredient to daily skincare products or sunscreens.
- Apigenin is a senescent cell clearing agent and exhibits significant absorption of ultraviolet UVB radiation;
- It also has soothing and reparative effects on skin problems such as inflammation, blistering, and keratosis;
- Apigenin can promote hair growth and improve the microenvironment of the scalp and hair follicles.
- It is added to products such as toothpaste and mouthwash to help improve oral problems such as gingivitis and mouth ulcers.
Applications of Apigenin-----Additives
Added as food additives to products such as food, supplements, and animal feed.
- It is added as an auxiliary ingredient to functional beverages, breakfast cereals, and other products to enhance the nutritional value and health benefits of ordinary foods;
- It is used as a main ingredient in the production of dietary supplements, including tablets and capsules, for daily health maintenance.For example, it can improve sleep quality, relieve anxiety, and enhance memory.
- It is an effective ingredient in functional pet foods, especially suitable for senior pets, and has the effect of supporting joint health and cognitive function；
- It is a green feed additive for livestock and poultry farming, which can not only replace antibiotics to promote animal growth but also improve the quality of meat, eggs, and milk；
- Whether for humans or animals, it offers a variety of benefits, including anti-inflammatory, antioxidant, neuroregulatory, and disease-preventive effects.
Applications of Apigenin-----Pharmaceutical Field
Primarily used in research and as candidate drug molecules.
- Apigenin,as a means of probing and interfering with intracellular signaling pathways in cancer cells, neurons, etc., it serves as a tool for understanding diseases (such as cancer and Alzheimer’s disease);
- Apigenin can be used in the development of new drugs with multiple targets and low toxicity (e.g., anticancer drugs, neuroprotective drugs, etc.);
- Apigenin has very poor oral absorption, making it a model drug for the development of novel drug delivery technologies (such as nanocarriers and liposomes);
- It is being tested as an additive ingredient in eye drops to alleviate eye discomfort such as dry eyes.
Dosage of Apigenin
The effects of Apigenin vary depending on the dosage. Apigenin supplements should not be used as a substitute for medication. Furthermore, if you are taking it for the first time, it is recommended to start with a low dose.
- ＜10mg，It has antioxidant and mild anti-inflammatory effects and can be obtained from a regular diet.
- 10-50mg，It has effects such as relaxing the mind, relieving anxiety, improving sleep quality, and maintaining cardiovascular health; this is the common dosage for most supplements.
- 50-100mg，It possesses significant anti-inflammatory effects, regulates blood lipids and blood sugar, protects the nervous system, and has potential as an adjunct in anti-tumor research. It should be used under the guidance of a physician.
- ＞100mg，It possesses potent anti-inflammatory effects, induces apoptosis in cancer cells, and acts as a chemosensitizer, and is widely used in cell and animal experiments.
Experimental studies have shown that Apigenin plays a role in testosterone synthesis. By supplementing with Apigenin, it increases testosterone levels and inhibits estrogen production, which helps in muscle growth and improved strength levels. It is widely used by fitness enthusiasts.
Apigenin-7-glucoside is a glycoside compound, a precursor of Apigenin, and one of the most abundant and common natural forms of Apigenin in plants.
Many common foods are rich in Apigenin, especially some herbs and specific fruits and vegetables. For example: parsley, celery leaves, chamomile; mint, perilla, thyme; oranges, grapefruit, etc.
Apigenin, Magnesium L-threonate, and L-theanine are a classic combination in mixed supplements. This combination is gentle, effective, and non-addictive, and has been shown to improve sleep, relieve anxiety, and promote relaxation.
Liposomal Apigenin refers to an Apigenin supplement manufactured using “liposomal” nanoparticle encapsulation technology, designed to improve the absorption rate and bioavailability of Apigenin in the body.
Side effects of Apigenin
- As an oral supplement, Apigenin is poorly absorbed; it is a lipid-soluble molecule with very low solubility in the intestines, causing most of the Apigenin to pass through the digestive tract as solid particles.
- As a dietary supplement, it is safe at regular doses. High doses may cause mild side effects, such as gastrointestinal discomfort, sedation or drowsiness, or some allergic reactions.
- When taken concurrently with certain medications such as antihypertensive drugs, antidiabetic drugs, and statins, interactions may occur, leading to poisoning or serious side effects, which can be life-threatening in severe cases.
- This product should be used with caution or under the guidance of a doctor by special populations, such as pregnant and breastfeeding women, children, individuals planning surgery, and those with severe liver or kidney disease.
