Physicochemical properties of Lauroyl Lysine
Appearance and Odor:White crystalline powder, odorless and tasteless
Solubility:Slightly soluble in water, sparingly soluble in common organic solvents such as ethanol and diethyl ether, and readily soluble in hot dimethylformamide (DMF)
Boiling Point:No definite boiling point (decomposes upon heating to approximately 230°C)
Melting Point:180-186℃
Density (at 20℃):1.03 g/cm³
Chemical Properties:
It possesses the structural characteristics of both amino acids and amides, exhibits excellent biocompatibility, and has good surface activity.
Under acidic/alkaline conditions, it can be hydrolyzed into lauric acid and L-lysine; the degradation products are safe and non-toxic.
Basic information about Lauroyl Lysine
Product Name：Lauroyl Lysine
Synonyms：N-Lauroyl-L-lysine、L-Lysine, N6-Dodecanoyl-L-lysine、N-6-Lauroyl-L-lysine、lauroyl lysine、N-Lauroyl-L-lysine、Lauroyl-Lysin、Lauroil-L-lisina
Abbreviation：LL
CAS No.:52315-75-0
EC No.:257-858-3
HS Code:2924199090(Note: This information may be verified and adjusted as needed in different regions.)
Molecular Formula:C18H36N2O3
Molecular Weight:328.49
Functional Group:Amide group (-CONH-), amino group (-NH2), carboxyl group (-COOH)
Chemical Category:It is a fatty acid amino acid derivative
Technical details of Lauroyl Lysine(additional information)
Production method: Synthesized by acylation reaction using L-lysine and lauroyl chloride as raw materials, followed by neutralization and purification; Purity grades: Industrial grade ≥98%, Cosmetic/Food grade ≥99%
Toxicological data:
Acute toxicity (LD50): Oral administration in rats > 5000 mg/kg (low toxicity)
Chronic toxicity: No significant toxicity with long-term exposure, no cumulative toxicity.
Safety limit (NOAEL): No specific daily allowable intake limit, meets food/cosmetic grade safety standards.
Upstream and downstream products:
Raw materials: L-lysine, lauroyl chloride, sodium hydroxide (neutralizing agent)
Downstream products: Cosmetics, food anti-caking agents, pharmaceutical preparations, personal care products
Relevant standards: Complies with GB 28303-2012 (food grade) and GB/T 29666-2013 (cosmetic grade); EU E172 food additive standard and REACH regulation registration requirements.
Storage & Package of Lauroyl Lysine
Storage: Lauryl lysine raw material should be stored in a cool, dry place in a sealed container, away from direct sunlight and high temperature and humidity. The shelf life is two years when unopened.
Packaging: Lauryl lysine raw material is packaged in 25kg/kraft paper bags (with PE film lining) or 50kg/cardboard drums; 1kg/5kg small sample packages are also available upon request.
Applications of Lauroyl Lysine
- Cosmetics and Personal Care: Lauryl lysine is primarily used in cosmetics and personal care products.
N-Lauroyl-L-lysine is used as an ingredient in cosmetic products such as foundations, loose powders, and eyeshadows, where it helps improve the product’s smoothness, spreadability, and long-lasting adherence. When added to creams, shampoos, and conditioners, it enhances the product’s moisturizing and nourishing effects.
Lauroyl Lysine, derived from natural amino acids and fatty acids, has good biocompatibility and is extremely low in irritation to the skin and eyes, making it suitable for cosmetic applications.
- Food Additives: Food-grade lauroyl lysine can be used as an anti-caking agent in powdered foods such as milk powder and seasonings to prevent powder clumping.
- Pharmaceutical and Medical Applications: Pharmaceutical-grade lauroyl lysine is used as an excipient in drug formulations, acting as a filler/flow agent to improve powder flowability and compressibility; it can also be used as a drug carrier, a surface modifier for medical materials, and an auxiliary agent for antibacterial agents; it can also be used in medical dressings and tissue engineering scaffolds to enhance biocompatibility.
- Industrial applications: Industrial-grade lauroyl lysine fundamentally alters the surface properties of solid particles such as powders, pigments, and fillers by forming a layer of oriented molecules on their surface. It is widely used in the production and processing of products such as coatings, inks, plastics, and specialty papers.
