Basic informaiton of Denatonium Benzoate
- Molecular Formula: C28H34N2O3
- Molecular weight: 446.59
- CAS No.: 3734-33-6
- EC No.: 223-095-2
- Package: 25kg/drum, 1kg/bag, 1kg/soluble bag, 100g/bottle, or as required by the customer.
- Store: Store in a tightly closed container.Store in a cool, dry area.
- Shelf life: 2 years.
- Synonyms: Benzenemethanaminium,N-(2-((2,6-dimethylphenyl) amino) -2-oxoethyl)-N, N-diethyl-,benzoate; Benzyldiethyl((2,6- xylylcarbamoyl) methyl) ammonium benzoate; Lidocaine benzyl benzoate; Q414815; FT-0622841; ST51007042; AMMONIUM,6-XYLYLCARBAMOYL)METHYL]-, BENZOATE; SY075333; A823606; DB-049095; W-106547; D2124; K-8241
What is Denatonium Benzoate?
Denatonium Benzoate is a white crystalline powder or granules, tasteless. Also known as Bitrex, it is the most bitter chemical substance in the world. If quinine has a bitterness level of 1, then Denatonium Benzoate has a bitterness level of 1000. To give a vivid example, a solution with a concentration of 10 ppm is unbearably bitter to humans. Denatonium Benzoate is often added in small amounts to liquids that are harmful to humans; its bitterness helps avoid accidental ingestion.
Denatonium Benzoate Solutions
Regular Package: 25kg, 200kg/drum.










Common Application of Denatonium Benzoate
Is Denatonium Benzoate toxic to dogs?Dogs are sensitive to denatonium. It can be applied to sofas and electrical wires to prevent them from being chewed on.
Small amounts of denatonium are not toxic to dogs, and ingestion of small amounts is safe.
Denatonium Benzoate and Nintendo SwitchNintendo Switch game cartridges are very tiny, and Nintendo has incorporated denatonate bezoate into the cartridge surface coating to prevent children from accidentally swallowing or licking the cartridges. The effect is excellent.
Prevention and control of plant diseases and pestsWatering or spraying plants with a suitable concentration of solution will make the leaves and branches taste bitter, deterring pests from eating them.
These methods are not only effective but also reduce pesticide use and protect the environment.
How to buy Denatonium Benzoate?
Highassay is one of the main Denatonium Benzoate suppliers in China. We offer Denatonium Benzoate pure powder and solutions. Highassay strictly controls quality, with over twenty years of production and operation experience, our product specifications almost meet all market demands. Customized specifications are welcome too. Please contact us for more information.


Denatonium Benzoate in Acetone
Almost all acetone products on the market contain a very small amount of Denatonium Benzoate.
This is because acetone is a colorless, transparent liquid and a widely used organic solvent in industry. To prevent improper use, such as accidental inhalation or ingestion, relevant regulations require the addition of a small amount of Denatonium Benzoate to acetone.
Specification of Denatonium Benzoate
- 20% in Ethylene Glycol Solution
- 25% in Ethylene Glycol Solution
- Propylene Glycol Water Solution
- Denatonium Benzoate USP Powder
| Products name : | Denatonium Benzoate 20% in Ethylene Glycol solution |
| Appearance | Colorless to yellowish liquid |
| Assay(Denatonium Benzoate ) | 20.0%min |
| PH | 6.8-8.0 |
| Chloride | 400ppm max |
| Products name : | Denatonium Benzoate 25% in Ethylene Glycol solution |
| Appearance | Colorless to yellowish liquid |
| Assay(Denatonium Benzoate ) | 24.5-26.5% |
| PH | 6.8-7.8 |
| Chloride | 500ppm max |
| Products name | Denatonium benzoate in Propylene Glycol water solution |
| Appearance | Colorless to yellowish liquid |
| Denatonium Benzoate | 39.5-41.5% |
| Water | ≤ 25.0% |
| Solidifying point | ≤ -40℃ |
| Items | Standards |
| Appearance | White powder |
| Identification | A) IR; B) UV; C) Test solution forms yellow precipitate D) Denatonium reinecate melting point: Approx 170℃ |
| Melting point | 163℃ to 170℃ |
| PH | 6.5 to 7.5 |
| Loss on drying | 1.0% max |
| Residual on ignition | 0.1% max |
| Chloride | 0.2% max |
| Assay | 99.5%~101.0% |
Bitrex is the trade name; its chemical name is Denatonium Benzoate. Compared to the chemical name, Bitrex is easier to pronounce and remember, and is widely known.
Denatonium Benzoate has low toxicity, an oral median lethal dose (LD50) of 485-740 mg/kg in rats.
Denatonium Benzoate is odorless.
Denatonium Benzoate is completely soluble in water.
Denatonium Benzoate melting point is 163 to 170°C.
Denatonium Benzoate is soluble in water, ether, ethylene glycol, propylene glycol, tert-butyl alcohol, and methanol. It is sparingly soluble in acetone and practically insoluble in ether.
Denatonium Benzoate does not have a precise boiling point because it decomposes before reaching a molten state. It decomposes between 180℃ and 220℃. Based on this, if a boiling point must be specified, it would be higher than 220℃.
Common Concerns
Cancer : LOW
Allergies & Immunotoxicity: LOW
Developmental and Reproductive Toxicity: LOW
Use Restrictions: LOW
Applications of Denatonium Benzoate
- A low-cost and highly effective substitute for strychnine (dimethylstrychnine), quassinolide, quinine, etc.
- The best alcohol denaturing agent;
- Applications in automotive chemicals, such as antifreeze, brake fluid, hydraulic fluid, battery electrolyte, ethanol gasoline, windshield washer fluid, and car polish;
- Applications in cosmetics and hair care products, such as hair dyes.
- Applications in household daily necessities. Examples of its applications include:
- Insect repellents, air fresheners, spray and scrub cleaning solutions, toilet cleaners, carpet, floor, and wall cleaners, dishwasher cleaners, leather cleaners and polishes, to prevent accidental ingestion and pet licking;
- Used in children’s toys, decorative items, and art paints to prevent children from chewing on toys and to prevent pets from licking toys and spreading pathogens; bittering in decorative items can prevent pets from licking and damaging them, and can also be used in decorative pine wood disinfectants to avoid mold growth.
- Used in pesticides, plant growth regulators, insecticides, rodenticides, molluscicides, and as bait for flies, ants, and cockroaches;
- Used in animal husbandry and veterinary medicine, and as a feed additive. Examples include: preventing cannibalism among pigs;
- Used in landscaping, agriculture, forestry, and environmental protection;
- Applications in military products such as communication cables and tear gas;
- Performance testing of gas masks and other applications;
How to remove Denatonium Benzoate from acetone
If the quantity is small, denatonium benzoate and acetone can be separated by distillation.
Another method is also available:
Due to the property that denatonium benzoate decomposes under high pH conditions, add a small amount of sodium hydroxide and water (to dissolve the sodium hydroxide) to the solution and wait for one hour for the denatonium benzoate to decompose.
Then cool the mixture to below 0°C. The water will freeze, and acetone, with a freezing point of -95°C, will remain liquid. The dissolved sodium hydroxide will precipitate to the bottom.
Then pour the acetone into another container; the separation is complete.
Femite is a famous brand of Denatonium Benzoate solution, which is used to discourage nail-biting and thumb-sucking habits.
Cats are sensitive to denatonium. It can be applied to sofas and electrical wires to prevent them from being chewed on.
Small amounts of denatonium are not toxic to cats, and ingestion of small amounts is safe.
Yes, Denatonium Benzoate is the bitterest substance known to humankind, and it is non-toxic, making it the most suitable substance for treating nail-biting. Years of market practice have proven its effectiveness.
Denatonium Benzoate cas 3734-33-6
Molecular Formula: C28H34N2O3
Denatonium Benzoate is added to nail polish remover to prevent children from biting their nails.
Highassay is one of the main Denatonium Benzoate manufacturers in China. Highassay has been supplying Denatonium Benzoate to both domestic and international markets, and has received high praise from our customers.
Denatonium Benzoate is mainly available in powder and solution forms, both of which Highassay manufactures regularly.
Highassay’s powder complies with USP/NF requirements. Please inquire about the purchase.
Highassay has been supplying Denatonium Benzoate for over twenty years. With industrial production, strict quality control, and competitive pricing, Highassay offers discounts for bulk purchases. Please inquire for more information.
It is added to rodenticides because humans are very sensitive to the taste of Denatonium Benzoate, while rats are not. Adding an appropriate dose of Denatonium Benzoate to rodenticides prevents accidental ingestion by humans while simultaneously killing rats.
Yes, low doses of Denatonium Benzoate are safe. Please refer to the information provided by EWG.
Yes, please refer to the MSDS link above.
Highassay supplies all kinds of Denatonium Benzoate solutions, including
Denatonium Benzoate 25% in Ethanol Solution
Denatonium Benzoate25% in Ethylene Glycol Solution
Denatonium Benzoate20% in Ethylene Glycol Solution
Denatonium Benzoate22.5% in Ethylene Glycol Solution
Denatonium Benzoate 25% in Propylene Glycol Solution
Denatonium Benzoate 40% in Propylene Glycol Water Solution
Denatonium Benzoate 40% in Tert Butyl Alcohol Water Solution
Denatonium Benzoate 40% in Methanol Solution
Denatonium Benzoate 4% in Water Solution
Denatonium Benzoate 2.5% in Water Solution
And any other solution formulations you desire.

No, Denatonium Benzoate is safe and low risk for cancer.
Denatonium Benzoate is stable at room temperature and does not readily evaporate.
For Denatonium Benzoate solutions, because many organic solvents, such as alcohol, are volatile, the lid should still be closed to maintain a sealed environment during storage.
No, Denatonium Benzoate is a low-risk carcinogen.
No, Denatonium Benzoate is unharmful.
Yes, Denatonium Benzoate is safe on skin.
Yes, Denatonium Benzoate is safe to consume
No, Denatonium Benzoate is non-toxic.
Highassay is a professional Denatonium Benzoate supplier in China; you may buy any Denatonium Benzoate powder and solution formulation from Highassay. Click to inquire now.






