A Brief Intoduction to Miconazole Nitrate
Molecular Formula:C18H15Cl4N3O4
Molecular Weight:479.141
CAS No.:22832-87-7
Appearance:White or off-white crystalline powder
Regular commercial package: 25kg/drum
What is Miconazole Nitrate?
Miconazole Nitrate is a topical antifungal medication used to treat deep fungal infections and localized fungal conditions. It is primarily used for oral infections caused by Candida albicans, vaginal problems caused by yeast or Candida, and fungal infections of the skin and mucous membranes, such as tinea pedis, tinea cruris, and tinea corporis. Miconazole Nitrate helps relieve itching, burning, or other discomfort caused by fungal infections.
Why choose Highassay?
Highassay provides high-purity, low-impurity Miconazole Nitrate powder, the main active ingredient in Miconazole Nitrate medications. Our products comply with multiple pharmacopoeias, including CP, BP, and USP, and meet GMP requirements. Highassay’s high-quality raw materials lay the foundation for your superior products. Miconazole Nitrate can be manufactured in various forms, the most common being ointment, but also including Miconazole Nitrate spray, Miconazole Nitrate powder, and in the form of intravenous infusion and suppositories, etc.
2% Miconazole Nitrate
2% Miconazole Nitrate is the proportion of 2% active pharmaceutical ingredient Miconazole Nitrate in a Miconazole Nitrate product, and this proportion is the verified optimal ratio. This approach maximizes the efficacy of Miconazole Nitrate while also protecting our skin from irritation.When you want to purchase this product yourself, you only need to confirm that the product contains 2% miconazole nitrate, which greatly solves your decision-making difficulties and also ensures the safety and effectiveness of the product you choose.Of course, as a manufacturer, using Highassay’s raw materials to produce 2% Miconazole Nitrate is also a good option.
Usage instructions and dosage recommendations of Miconazole Nitrate
Miconazole Nitrate in cream form is the most common and frequently used form of this medication, and it is essential to fully understand its usage and dosage. Incorrect usage and inappropriate dosage can easily cause adverse reactions, such as local stinging and itching; in more severe cases, it can cause systemic rashes, urticaria, etc.; long-term use can damage the skin barrier, etc.
- For tinea corporis and tinea pedis: Apply a thin layer to the affected area twice daily for approximately four weeks.
- For tinea cruris: Apply externally twice daily for approximately two weeks.
- For Vulvovaginal candidiasis: With the aid of an applicator, squeeze about 5 grams of ointment deep into the vagina and use it continuously for two weeks.
Miconazole Nitrate for Dogs
Compound Miconazole ear drops for dogs are also a formulation of Miconazole Nitrate, mainly composed of hydrocortisone acetate propyl ester, miconazole nitrate, and gentamicin sulfate.It is a white suspension, primarily used for canine otitis externa caused by fungal infections such as Malassezia furfur or recurrent canine otitis externa.Before use, you should clean the dog’s external ear canal and trim any nearby hair to facilitate medication application. Use the recommended dosage for best therapeutic effect.
Specification of Miconazole Nitrate
- Specification of Miconazole Nitrate
| Product Name | Miconazole Nitrate |
| Odor | Odorless |
| Density | 1.451g/cm³ |
| Melting Point | 170-185℃ |
| Boiling Point | 555.1℃ |
| Flash Point | 289.5℃ |
| Solubility | Slightly soluble in methanol, sparingly soluble in chloroform or ethanol, and insoluble in water or ether. |
| Storage | Store in a light-proof and airtight container |
First, their main components are different, and Clotrimazole has weaker penetration. Second, Miconazole Nitrate has a broader antibacterial spectrum than Clotrimazole, primarily targeting different types of diseases. Finally, the two antibiotics have different adverse reactions.
Although both are broad-spectrum bactericides, tonaphalate is ineffective against Candida and bacterial infections.
Ticonazole is mainly used to treat vaginal yeast infections, while Miconazole Nitrate has a wider range of applications.
About Miconazole Nitrate
- Miconazole Nitrate is a broad-spectrum antifungal drug that works by inhibiting the synthesis of fungal cell membranes, disrupting the integrity of fungal cells, and causing them to die.
- When using Miconazole Nitrate ointment or suppositories vaginally, it is recommended to continue using the medication during menstruation to maintain its effectiveness, and pay attention to hygiene. It can also be continued even in the event of a recurrence.
- If your fungal infection has improved significantly, please continue using it for a period of time to prevent a recurrence.
- Miconazole Nitrate oral patches or gels are prescription drugs, while other forms of preparations (ointments, sprays, soft capsules, etc.) are over-the-counter drugs.
- Miconazole Nitrate should be stored in a dark place out of reach of children and sealed in a container.
How to judge the effectiveness of Miconazole Nitrate?
- The speed at which the medication takes effect depends on the severity of your infection, the specific location of the infection, and your absorption rate of the medication. The treatment effect varies from person to person.
- Mild cases generally show symptom improvement within about 3 days; severe cases and those with recurrent infections may take longer.
- If your condition does not improve after about a week of medication, please stop taking the medication, as the medication you have chosen may not be effective for your condition.
- If you experience a severe allergic reaction during use, please clean the application site immediately, stop using the medication, and consult a doctor.
