What is Alpha Lipoic Acid?
Alpha Lipoic Acid is an organic compound and a powerful antioxidant found naturally in the human body. While the body can synthesize it naturally, its ability to synthesize it decreases with age, necessitating its acquisition through food or supplements. For the average person, supplemental Alpha Lipoic Acid is not necessary; it can be obtained naturally through foods like spinach, broccoli, and organ meats. The Alpha Lipoic Acid raw materials provided by Highassay are not only used in dietary supplements but are also utilized in various fields, such as medicine, cosmetics, and biotechnology.
Benefits of Alpha Lipoic Acid
- Because Alpha Lipoic Acid is both fat-soluble and water-soluble, it reaches all parts of the body after absorption, improving its absorption efficiency. It plays a significant role in energy metabolism, neuroprotection, and anti-aging.
- Alpha Lipoic acid is a coenzyme found in mitochondria and a versatile antioxidant and anti-inflammatory agent, similar to vitamins.
- Alpha Lipoic acid helps improve neuropathy by scavenging free radicals, protecting mitochondria, and promoting the synthesis of neurotrophic factors.
- As a dietary supplement, Alpha Lipoic Acid is effective for weight loss, liver protection, and cognitive development, and its effects are mild and non-irritating.
- Alpha Lipoic Acid is commonly found in foods, making it easy to obtain the required dose.

Why choose Highassay's Alpha Lipoic Acid?
Highassay’s Alpha Lipoic Acid offers the following advantages: enhanced biological activity; high product stability; no toluene; and solvent-free options. In addition to the product’s inherent advantages of high yield and low impurity content, Highassay partners with one of the world’s largest R&D and manufacturing companies, ensuring the support of an integrated supply chain. Highassay’s team is committed to providing you with the highest quality service, competitive pricing, and comprehensive after-sales support.
Highassay adheres to strict quality control (QC) to produce Alpha Lipoic Acid. Buy Alpha Lipoic Acid in bulk from us now to get competitive market prices.
Applications of Alpha Lipoic Acid
If you have any questions about processing Alpha Lipoic Acid, Highassay’s R&D team is here to help.
MedicalIt is formulated as an oral, injectable, and infusion solution for treating a range of chronic conditions, such as brain disorders and cardiovascular disease. It is particularly effective for diabetes and its complications. The oral dosage is approximately 600 mg per day, while infusion and injection solutions may show results more quickly.
Food AdditiveAlpha Lipoic Acid is used as an additive in dietary supplements and health products and can be formulated in capsules, tablets, and softgels. Its primary benefits include scavenging free radicals, protecting nerve health, and maintaining metabolism.It can also be added to food and beverages as a food additive to improve nutritional value.
CosmeticsResearch has found that addingAlpha Lipoic Acid, which contains strong antioxidant properties, to creams, essences and other cosmetics and applying them on the skin can reduce wrinkles, improve rough skin, and can integrate into the inner layer of the skin, effectively protecting against ultraviolet radiation and effectively delaying skin aging.
Highassay's Lipoic Acid Product Types
Highassay’s Lipoic Acid products include Alpha-Lipoic Acid, R-Lipoic Acid, and R-Lipoic Acid Sodium Salt.
- Comparison of Alpha-Lipoic Acid and R-Lipoic Acid
| Characteristic | R-ALA | ALA |
| Melting Point | 47℃-49℃ | 60℃-62℃ |
| Specific Rotation | +80-90° | ±1 |
| Existence in Nature | exist | does not exist |
| Chirality | Chiral substances | Achiral substances |
| Biological Activity | High | Low |
| Antioxidant Function | High | Low |
| Anti-inflammatory Activity | 10 | 1 |
- Sodium lipoate is the sodium salt form of lipoic acid, containing 82% lipoic acid. The sodium salt form increases solubility in water, making the product more stable and easier for the body to absorb.

Specification of Alpha Lipoic Acid
- Specification of Alpha Lipoic Acid
- Certificate of Analysis for Alpha Lipoic Acid
| Product Name | Alpha Lipoic Acid |
| CAS No. | 1077-28-7 |
| Appearance | Slightly yellow crystalline powder |
| Molecular Formula | C9H1805S2 |
| Molecular Weight | 206.3 g/mol |
| Melting Point | About 60.5°C |
| Solubility | Insoluble in water, soluble in ethanol, methanol and diethyl ether |
| Items | Specifications | Results | Test Method |
| Appearance | Slightly yellow crystalline powder | Passes | Organoleptic |
| Assay (HPLC) | 99.0% -101.0% | 99.50% | USP |
| Bulk Density | ≥0.300 g/ml | 0.382 g/ml | GB/T 20316.2-2006 |
| Tapped Density | ≥0.450 g/ml | 0.504 g/ml | GB/T 21354-2008 |
| Melting Temperature | 60.0℃- 62.0℃ | 60.6℃ | USP |
| Individual Impurity | ≤ 0.1% | 0.06% | USP |
| Total Impurities | ≤ 2.0% | 0.06% | USP |
| Impurity Polymer(TLC) | ≤ 1.0% | Passes | USP |
| Particle Size | 100% thru #40 mesh | Passes | GB/T13025.1-2012 |
| Loss On Drying | ≤ 0.2% | 0.14% | USP |
| Residual on Ignition | ≤ 0.1% | 0.03% | USP |
| Specific Rotation[α] | -1.0°-+1.0° | 0° | USP |
| Heavy Metals (as Pb) | ≤ 10ppm | ≤ 10ppm | General Rule 0821 |
| Lead (Pb) | ≤ 0.5ppm | ND | ICP-MS |
| Cadmium (Cd) | ≤ 1ppm | ND | ICP-MS |
| Mercury (Hg) | ≤ 0.1ppm | 0.00757ppm | ICP-MS |
| Arsenic (As) | ≤ 1ppm | 0.0202ppm | ICP-MS |
| Cyclohexane | ≤ 3880ppm | 891ppm | USP |
| Ethyl Acetate | ≤ 5000ppm | 337ppm | USP |
| Total Aerobic Count | ≤ 1000 cfu/g | < 10 cfu/g | GB 4789.2-2022 |
| Molds and Yeasts | ≤ 100 cfu/g | < 10 cfu/g | GB 4789.15-2016 |
| Total Coliforms | ≤ 100 cfu/g | < 10 cfu/g | GB 4789.3-2016 |
| Escherichia Coli | Negative to test (<10 cfu/g) | < 10 cfu/g | GB 4789.38-2012 |
| Salmonella Species | Negative to test (Absent in 25g) | Absent in 25g | GB 4789.4-2024 |
| Staphylococcus Aureus | Negative to test (Absent in 25g) | Absent in 25g | GB 4789.10-2016 |
| Conclusion: This Batch of Product Complies with current USP standard. | |||
Product prices vary due to market fluctuations. Please contact customer service for pricing before purchasing. We will provide you with the best price and the best product quality.
We have a comprehensive supply chain system with rigorous inspection processes from packaging to shipping to ensure that your products reach you safely and intact. Your satisfaction is our ultimate goal.
We ship within 1-3 days. You can specify your preferred shipping method and offer expedited service.
Notes on Alpha Lipoic Acid
Alpha Lipoic Acid is suitable for:
- People who love sports and exercise a lot: it helps with rapid recovery.
- People with cognitive impairment or dementia: it helps regulate brain nerves.
- People with weak liver and heart function: it helps increase antioxidant enzyme levels.
- People with unstable blood sugar levels: it helps improve insulin resistance and sensitivity.
People who should not take Alpha Lipoic Acid supplements:
- If you are taking other medications, consult your doctor to determine if lipoic acid may interfere with or reduce the effectiveness of your medications.
- If you are diabetic, Alpha Lipoic Acid supplements are not recommended, as high levels in the body may interfere with normal blood sugar regulation.
- If you have allergies, it may cause an allergic reaction.
- If you are healthy and do not have special needs, supplementation is not necessary without a doctor’s advice. Pregnant women, breastfeeding women, children, and those with renal impairment should not take lipoic acid supplements.
Side effects of Alpha Lipoic Acid:
Alpha Lipoic Acid supplementation in moderation or as directed by a doctor generally does not cause any side effects. However, excessive or high oral doses may cause mild stomach discomfort, nausea, and rash in some people.





